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Example sentences for: lrat

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Reciprocal searches initiated with regions from the newly detected proteins YaeF, LRAT and LytN detected their closely related homologs in the initial iterations, but in subsequent iterations they recovered several classic N1pC/P60 homolog members with significant E-values (E < 0.01),
This feature is even observed in the NlpC/P60 superfamily, including the insertion of an entire zinc ribbon domain [ 47] in the case of the plant homologs of LRAT.
The LRAT family is thus far found only in eukaryotes and animal viruses, with the sole exception of a single member from the proteomes of Vibrio cholerae and Anabaena . The LRAT and its obvious orthologs are found, in addition to the vertebrates, in other animals and plants.
Hence, the LRAT family was probably acquired by the eukaryotes, by the lateral transfer of a bacterial precursor similar to the YaeF/YiiX family.
Interestingly, the eukaryotic versions typified by the LRAT, their viral homologs and the bacterial forms typified by E. coli YaeF, while containing all the hallmark signatures of the NlpC/P60 catalytic domain, showed a reversal in the positions of the motifs with the conserved cysteine and the conserved histidine in their primary structures (Figures 1, 2).