Words similar to lqs
Example sentences for: lqs
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Of the 6,525 human and 566 mouse EST libraries considered, 899 and 176, respectively, had an LQS of greater than 0.95, indicating that these libraries were generated by an efficient method of directional cloning.
A full list of the mouse and human EST libraries and their LQS scores is available at our website [ 22].
The remainder of our analysis focused exclusively on the 1,151,724 human ESTs and 550,567 mouse ESTs derived from the libraries with LQS scores of greater than 0.95.
We therefore revised our analysis to calculate LQS scores exclusively from UniGene clusters whose BOU representative was an mRNA with an annotated ORF window (indicating that the BOU is deposited in the correct orientation).
The results of this analysis on the human EST dataset are shown in Figure 1. In our final analysis (green bars in Figure 1), the distribution of LQS scores across the full set of UniGene EST libraries is roughly bimodal, with a peak near LQS = 0.5 (random orientation of ESTs) and a peak near LQS = 1.0 (correct orientation of nearly all ESTs).