Words similar to lpa

Example sentences for: lpa

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Lysophophatidic Acid (LPA) is a member of this class of compounds, and its plasma levels have been proposed as a potential biomarker for ovarian cancer [ 16 17 ] . LPA is a family of related molecules with molecular weights in the vicinity of 400 to 600 Daltons, and a variety of LPA species has been reported to be increased in malignant ascites from patients with ovarian cancer as detected by electrospray ionization mass spectrometry (ESI-MS) [ 18 ] . LPA related species have also been reported to be increased in plasma samples from patients with ovarian cancer using a combination of thin layer chromatography (to isolate an "LPA band" from patient plasma) followed by ESI-MS.
In the case of LPA, increased plasma levels may be associated with platelet activation.
This study reported significant LPA increases in cancer samples with increased intensities noted at M/Z values of 409, 433-437, 457, 481-482, 571, 599, and 619.
However, it is possible that in some cases they may relate to the LPA family of molecules, or to alterations in proteins that bind LPA family members.
LPA) is a member of a pathway altered during serum sample collection, changes between plasma levels of cancer and control subjects may be obscured.