Words similar to lpa

Example sentences for: lpa

How can you use “lpa” in a sentence? Here are some example sentences to help you improve your vocabulary:

, [ 27 ] reported that endogenously-expressed LPA and endothelin-1 (ET-1) receptors in SK-N-MC cells do not activate ERKs unless the EGFR is co-expressed, although each GPCR is functional as evidenced by their ability to increase intracellular [Ca 2+].
However, it is possible that in some cases they may relate to the LPA family of molecules, or to alterations in proteins that bind LPA family members.
Another group trying to repeat the observations of increased levels of LPA associated with ovarian cancer concluded that there was no diagnostic value in the assay, and attributed the discrepant findings as possibly related to different sample centrifugation protocols used by the two groups to remove platelets from the samples prior to analysis [ 20 ] . However, LPA continues to be actively evaluated for its clinical utility [ 21 ] .
In the presence of the EGFR, ligand activation of LPA and ET-1 receptors did not increase EGFR phosphorylation even though both the LPA and ET-1 receptors stimulated ERK activity by 10-fold over basal [ 27 ] . Specifically, key protein intermediates may be physically associated with endogenous RTKs in HEK-293 cells, and therefore, down-regulation of the EGFR may negatively affect ERK phosphorylation by opioids.
This report also reviews the evidence that these M/Z values are consistent with LPA family members [ 19 ] . Figure 4shows the average intensities and p-values for both the cancer and control groups in the region between M/Z values of 410 to 470.