Words similar to lfc
Example sentences for: lfc
How can you use “lfc” in a sentence? Here are some example sentences to help you improve your vocabulary:
This indicates that a 5% LFC model is confidently selecting differentially regulated genes across the full range of absolute expression.
This method moves beyond setting a single fold change cut-off by considering fold change in the context of absolute expression [ 27 ] . In brief, this method includes: (A) the determination of the upper 5% of fold changes within narrow bins of absolute expression levels to determine a limit fold change (LFC) function; and (B) subsequent ranking of genes by a combined fold change/absolute difference calculation.
Lastly it should be noted that the LFC, i.e. the modeled trend of HFC vs. min ADI, is based on binned data of hundreds of genes across multiple conditions leading to a highly powerful characterization of a given threshold.
When interested in the top 5% and 1% of significant genes, the total number of genes that meet the LFC requirements is 471 and 82, respectively.
Figure 1bshows that as the selection criteria becomes more strict (top 5% → 1% of genes), the curve shifts (1% LFC model = 2.43 + 166.
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