Words similar to lewy
Example sentences for: lewy
How can you use “lewy” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, it is not clear whether all the genetic diseases given PARK nomenclature have Lewy bodies and should be considered “true” PD—the term parkinsonism is preferred for these syndromes (Hardy and Langston 2004).
Whether the Lewy body is damaging or neuroprotective, there are clearly several possible targets for toxic α-synuclein within the cell.
The phenotype of patients with α- synuclein mutations varies from PD to a more diffuse Lewy body disease in which pathology is detected in the cerebral cortex and other areas of the brain.
It is generally assumed that fibrils are the form of α-synuclein deposited into Lewy bodies, but whether Lewy bodies damage cells is controversial.
The fact that the wild-type protein can aggregate suggests that the process is fundamentally similar for both inherited and sporadic PD in which wild-type α-synuclein is also present in Lewy bodies.