Words similar to lewy
Example sentences for: lewy
How can you use “lewy” in a sentence? Here are some example sentences to help you improve your vocabulary:
One possibility is that by sequestering α-synuclein into this insoluble body and compartmentalizing the potentially toxic species away from possible targets in the cytoplasm, the Lewy body represents an attempt of the cell to protect itself (Olanow et al.
For example, it is not clear whether all the genetic diseases given PARK nomenclature have Lewy bodies and should be considered “true” PD—the term parkinsonism is preferred for these syndromes (Hardy and Langston 2004).
It is generally assumed that fibrils are the form of α-synuclein deposited into Lewy bodies, but whether Lewy bodies damage cells is controversial.
The fact that the wild-type protein can aggregate suggests that the process is fundamentally similar for both inherited and sporadic PD in which wild-type α-synuclein is also present in Lewy bodies.
Whether the Lewy body is damaging or neuroprotective, there are clearly several possible targets for toxic α-synuclein within the cell.
Loading...