Words similar to lewy
Example sentences for: lewy
How can you use “lewy” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is generally assumed that fibrils are the form of α-synuclein deposited into Lewy bodies, but whether Lewy bodies damage cells is controversial.
The phenotype of patients with α- synuclein mutations varies from PD to a more diffuse Lewy body disease in which pathology is detected in the cerebral cortex and other areas of the brain.
Named after their discoverer, these “Lewy bodies” are one piece of evidence that protein aggregation is related to the ongoing disease process.
The fact that the wild-type protein can aggregate suggests that the process is fundamentally similar for both inherited and sporadic PD in which wild-type α-synuclein is also present in Lewy bodies.
One possibility is that by sequestering α-synuclein into this insoluble body and compartmentalizing the potentially toxic species away from possible targets in the cytoplasm, the Lewy body represents an attempt of the cell to protect itself (Olanow et al.
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