Example sentences for: leptin

How can you use “leptin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • On the other hand, blocking the rise in corticosterone by adrenalectomy prevented the reduction in hypothalamic POMC mRNA and the induction of AGRP mRNA, without reversing either the reduced leptin or the reduced adiposity, characteristic of insulin-deficient diabetic mice (Fig.

  • In unadjusted models, leptin was significantly correlated with total sleep time and average weekly sleep with naps, and ghrelin was significantly correlated with sleep efficiency and WASO.

  • Leptin production is primarily regulated by insulin-induced changes in adipocyte metabolism—its secretion levels correlate with adipocyte mass and lipid loads.

  • Ming Li and his colleagues at the University of Texas in San Antonio, Texas, are studying nicotine's effects on weight and on expression of genes that nicotine upregulates orexin and neuropeptide Y and, more recently, that it also regulates leptin signaling.

  • Obesity or higher body mass index have been implicated by some but not other studies as risk factors for increased IOP and glaucoma [ 51 55 56 57 ] . Similarly, diabetes or the combination of diabetes and obesity have been variably associated with elevated IOP and glaucoma [ 46 52 58 59 60 61 62 ] . To test if genetic perturbations that cause obesity and diabetes can alter IOP, we compared groups of mice that were genetically similar except that they were either homozygous or heterozygous for a leptin receptor mutation ( db ) that results in early onset obesity and diabetes.


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