Words similar to latency
Example sentences for: latency
How can you use “latency” in a sentence? Here are some example sentences to help you improve your vocabulary:
People move between ZIP codes and cancer latency (the time between causative exposures and cancer onset) is estimated to be between 5-40 years for these cancers, so the ZIP code where the patient was diagnosed may not be the location where the cancer developed nor where causative exposures occurred.
CMV invades the vascular endothelium with the development of both latency and intermittent shedding of the virus to distal tissues, often by detachment of infected endothelial cells.
In vivo , it would be difficult to pinpoint one specific factor to cause the switch from latency to lytic infection.
CMV, a herpes virus, causes chronic asymptomatic infections in immunocompetent individuals, termed latency [ 13 ] . However, in situations of immunocompromise, CMV is reactivated, which in many cases leads to organ failure and death [ 13 ] . Epidemiological reports indicate that chronic CMV infections in humans may play an important role in pathogenesis of vascular diseases such as atherosclerosis [ 14 ] and systemic sclerosis [ 11 12 ] . In addition, a recent report [ 15 ] revealed that SSc autoantibodies bind to CMV late protein UL94 and induce apoptosis in endothelial cells therefore implicating molecular mimicry as a potential mechanism accounting for the link between SSc and CMV.
Similarly, inositol 1,4,5-trisphosphate receptors (IP3R) are intracellular calcium release channels involved in diverse signaling pathways and are required for the activation of T lymphocytes [ 33 ] . Tat (also implicated as a neurotoxin) has been shown to release calcium from inositol 1,4, 5-trisphosphate (IP3) receptor-regulated stores in neurons and astrocytes causing premature apoptosis [ 34 ] . Down-regulation of IP3 may therefore contribute to viral latency and maintenance of an anti-apoptotic state in cells.
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