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Example sentences for: lamins

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The four conserved sequence motifs identified in the FPP family appear to be unique to this group of coiled-coil proteins and are neither shared by other coiled-coil open reading frames present in the Arabidopsis genome nor by coiled-coil proteins such as lamins from other organisms.
The nuclear lamins contain short, conserved sequences flanking the lamin rod domain, which are phosphorylated by cdc2 kinase [ 41 ] . The 90 amino acid PACT domain, which immediately follows the coiled-coil domain of the related proteins pericentrin and AKAP450 and two uncharacterized coiled-coil open reading frames from Drosophila and Schizosaccharomyces pombe , confers centrosomal localization [ 19 ] . A conserved domain of ca. 50 amino acids was found in several Golgi-associated large coiled-coil proteins.
It is therefore likely that non-animal eukaryotes have a distinct set of nuclear envelope proteins that functionally replace the lamins.
The Drosophila mutations Mushroom body defect (a gene involved in the proliferation of neuronal precursor cells) and quick-to-court (a mutation that causes elevated sexual behavior) lie in two tissue-specifically expressed coiled-coil proteins of unknown function [ 20 21 ] . In humans and mouse models, specific point mutations in nuclear lamins are the cause for autosomal Emery-Dreifuss muscular dystrophy [ 22 23 ] .
SMI-31 and RT-97 also revealed a band or closely spaced bands at 70 kDa which corresponds approximately to the MW of lamins.