Words similar to lamin

Example sentences for: lamin

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Our findings demonstrate a novel mutation in lamin A/C in a proband whose family was previously linked to DCM with conduction disease and chromosome 1q21.
Of note, mice with a null allele in lmna display a phenotype only in the homozygous state [ 22 ] . The mutation we now describe is predicted to generate a substantial protein fragment consisting of the first 37 KDa of lamin A/C.
Interestingly, analysis of Lamin beta 2 origin of replication region also revealed the presence of two ACS (9/11 match) like elements [ 17 ] . Further studies are required to find out whether p35 also binds to lamin beta 2 origin region.
The nuclear lamins contain short, conserved sequences flanking the lamin rod domain, which are phosphorylated by cdc2 kinase [ 41 ] . The 90 amino acid PACT domain, which immediately follows the coiled-coil domain of the related proteins pericentrin and AKAP450 and two uncharacterized coiled-coil open reading frames from Drosophila and Schizosaccharomyces pombe , confers centrosomal localization [ 19 ] . A conserved domain of ca. 50 amino acids was found in several Golgi-associated large coiled-coil proteins.
The specificity of dsRNA activity was further tested by using a dsRNA against cellular lamin A/C that was earlier shown to specifically abrogate lamin A/C synthesis in a variety of cultured cell lines [ 2 ] . As shown in Fig.