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Example sentences for: lak
How can you use “lak” in a sentence? Here are some example sentences to help you improve your vocabulary:
I remembah dat day jes lak it was yestiday.
Both precursor and effector cells of this activity were typically NK cells [ 11 ] . Direct evidence that NK cells are the mediators of LAK activity came from Immunotransmission Electron microscopic studies using colloidal gold labeled antibodies in which CD16 positive cells were shown to extend their protrusions deep into the target cells and it was found that the cytoplasmic granules and vacuoles of CD16 positive LAK cells were concentrated in the area of the binding site [ 12 ] . With the advent of flowcytometry and immunophenotyping we thought we could approach this dilemma in a different but simple and straightforward manner.
Following low dose IL-2 treatment in leprosy patients, NK cell numbers were found to increase 6-fold and IL-2 therapy of HIV patients resulted in enhanced NK and LAK cell activity in vitro [ 18 ] IL-2 subcutaneously given resulted in, in vivo expansion of CD16 positive NK cells to very large numbers which showed LAK activity and ADCC (Antibody Dependent Cellular Cytotoxicity) in vitro [ 19 ] . In view of the above mentioned and other reports available in literature, a pilot study was undertaken to see the effect of IL-2 and/or IL-12 stimulation on a long term basis and study the phenotypic changes corresponding to the cytotoxic changes after in vitro culture of the peripheral blood lymphocytes.
This has been referred to as the LAK phenomenon [ 1 ] . Similarly IL-12 treatment of peripheral blood mononuclear cells (PBMC) or pure NK cells within a few hours, induces, an enhancement of cytotoxic ability.
LAK - Lymphokine Activated Killer
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