Example sentences for: lak

How can you use “lak” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Following low dose IL-2 treatment in leprosy patients, NK cell numbers were found to increase 6-fold and IL-2 therapy of HIV patients resulted in enhanced NK and LAK cell activity in vitro [ 18 ] IL-2 subcutaneously given resulted in, in vivo expansion of CD16 positive NK cells to very large numbers which showed LAK activity and ADCC (Antibody Dependent Cellular Cytotoxicity) in vitro [ 19 ] . In view of the above mentioned and other reports available in literature, a pilot study was undertaken to see the effect of IL-2 and/or IL-12 stimulation on a long term basis and study the phenotypic changes corresponding to the cytotoxic changes after in vitro culture of the peripheral blood lymphocytes.

  • Straightforward enough is The neighbour before the house, the companion before the road [ al-jaar qabl ad-daar, ar-rafiiq qabl aT-Tariiq ], friendship and rhyme going hand in hand as in He who loves you will chew pebbles for you, your enemy will count your faults [Habiibutak yamDugh lak azzalaT wa \?\aduuka ya\?\ud al-ghalaT ].

  • LAK cells were generated as described.

  • It may be that the various lymphokine growth factors are differentially produced at different time points during the ontogeny of the immune system at different stages in the development of an immune response or at different sites within the body or lymphoid tissues [ 30 ] . Our studies have confirmed the importance of multiple cytokine stimulation of lymphocytes and how NK cells are crucial to the development of spontaneous cytotoxicity and are the major contributors to LAK activity in vitro when U-937 cells were used as targets.

  • Some researchers have reported the ability of CD56 positive T cells to exhibit spontaneous killing against some of the targets such as K562 or P815, upon stimulation with IL-2 [ 22 23 24 25 ] . However Lanier and Philips who carried out extensive studies on the LAK phenomenon have emphasised that although CD16+ T cells exhibit non-MHC-restricted cytotoxicity to some targets upon IL-2 stimulation, their contribution was quantitatively and qualitatively very minimal as compared to the NK subset [ 7 11 ] . The differences in the ability of lymphocytes of different phenotypes to respond to IL-2 stimulation and carry out spontaneous lysis of different targets could probably be attributed to the differential expression of inhibitory receptors present on the targets such as KIR and CD94:NKG2 [ 26 ] .


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