Words similar to lak
Example sentences for: lak
How can you use “lak” in a sentence? Here are some example sentences to help you improve your vocabulary:
It may be that the various lymphokine growth factors are differentially produced at different time points during the ontogeny of the immune system at different stages in the development of an immune response or at different sites within the body or lymphoid tissues [ 30 ] . Our studies have confirmed the importance of multiple cytokine stimulation of lymphocytes and how NK cells are crucial to the development of spontaneous cytotoxicity and are the major contributors to LAK activity in vitro when U-937 cells were used as targets.
LAK cells were generated as described.
Both precursor and effector cells of this activity were typically NK cells [ 11 ] . Direct evidence that NK cells are the mediators of LAK activity came from Immunotransmission Electron microscopic studies using colloidal gold labeled antibodies in which CD16 positive cells were shown to extend their protrusions deep into the target cells and it was found that the cytoplasmic granules and vacuoles of CD16 positive LAK cells were concentrated in the area of the binding site [ 12 ] . With the advent of flowcytometry and immunophenotyping we thought we could approach this dilemma in a different but simple and straightforward manner.
Therefore we generated LAK cells by the method of Anita and Hersh [ 13 ] and carried out cytotoxicity experiments with the stimulated cells.
This has been referred to as the LAK phenomenon [ 1 ] . Similarly IL-12 treatment of peripheral blood mononuclear cells (PBMC) or pure NK cells within a few hours, induces, an enhancement of cytotoxic ability.
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