Words similar to laglidadg

Example sentences for: laglidadg

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At least the former, and perhaps even the latter, appear to belong to a large class of nucleic-acid-binding domains that includes the APSES, LAGLIDADG endonuclease and TEN domains.
A search with the APSES domain (PDB 1bm8) using the VAST program [ 22] detected significant structural alignments with both the LAGLIDADG and the TEN domains ( p approximately 10 -4).
These observations suggest that the APSES, LAGLIDADG and TEN domains, together with the KilA-N domain, define a novel nucleic-acid-binding fold with a conserved (β 2 α) 2 core (Figure 1b).
The KilA-N, APSES and TEN-terminal domains lack the equivalent residues of the specific active-site extension of the LAGLIDADG nucleases, suggesting that the former domains do not possess nuclease activity.
Like the KilA-N domains that are mainly associated with DNA viruses, the LAGLIDADG endonucleases are predominantly encoded by mobile genetic elements [ 31].