Words similar to lactase
Example sentences for: lactase
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In other conditions with chronic diarrhea, such as inflammatory bowel disease, renal stones have been composed of calcium phosphate or oxalate [ 32 ] . Alternatively, it is possible that both SI and lactase are connected mechanistically to intestinal calcium homeostasis through molecular interactions with calcium transporters.
In that study, two adults presented with renal calculi and nephrocalcinosis [ 3 ] . Lactase deficiency may give rise to metabolic bone disease [ 31 ] . More pertinently, Saarela et al described 7 of 10 infants with congenital lactase deficiency who had hypercalcemia at the time of initial presentation [ 4 ] . Five of these 7 infants had medullary nephrocalcinosis.
Sucrase deficiency may be especially common in indigenous Greenlanders (estimated 5%) and is accompanied most often by lactase deficiency [ 24 25 ] . Initial studies demonstrated that most SI mutations result in lack of enzyme protein (i.e.
In contrast, hypercalcemia frequently complicates congenital lactase deficiency [ 4 ] . The present case illustrates the occurrence of hypercalcemia and nephrocalcinosis as a clinically significant complication of SI deficiency in an infant and suggests that common mechanisms may lead to hypercalcemia in both SI and congenital lactase deficiency.
Small bowel biopsies taken at the time of endoscopy revealed: lactase 34.