Words similar to lactacystin

Example sentences for: lactacystin

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The receptor activation-induced decrease of SNIP1 is partially sensitive to the proteasome-specific inhibitor lactacystin, suggesting the involvement of proteasomal degradation (Fig.
When proteasome inhibitors were applied, the inhibitors LLnL (50 mM in DMSO) or lactacystin (10 mM in H 2 O) were added directly to the cell medium at 1:1000 dilutions.
When the activated BMP type I receptor was co-expressed with Smad1 and HsN3, a reduction of Smad1 level was detected and the reduction is blocked by the addition of the proteasome inhibitor lactacystin, indicating the proteasomal degradation of Smad1 induced by BMP type I receptor activation.
This phenomenon was further investigated and confirmed in a separate study [ 39 ] . The interaction between Pro-N3-F and Smad1 was also stabilized in the presence of proteasome inhibitor lactacystin (Fig.
The incomplete rescue of SNIP1 level by lactacystin suggests the involvement of additional mechanisms other than 26S proteasome in SNIP1 degradation.