Words similar to lactacystin

Example sentences for: lactacystin

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This phenomenon was further investigated and confirmed in a separate study [ 39 ] . The interaction between Pro-N3-F and Smad1 was also stabilized in the presence of proteasome inhibitor lactacystin (Fig.
When the activated BMP type I receptor was co-expressed with Smad1 and HsN3, a reduction of Smad1 level was detected and the reduction is blocked by the addition of the proteasome inhibitor lactacystin, indicating the proteasomal degradation of Smad1 induced by BMP type I receptor activation.
When proteasome inhibitors were applied, the inhibitors LLnL (50 mM in DMSO) or lactacystin (10 mM in H 2 O) were added directly to the cell medium at 1:1000 dilutions.
In contrast, TBP and TAF II 135 are readily detected in extracts made from differentiated cells treated with MG132, ALLN, and the proteasome-specific inhibitor lactacystin (our unpublished data) showing that their disappearance is due to selective proteolysis.
The receptor activation-induced decrease of SNIP1 is partially sensitive to the proteasome-specific inhibitor lactacystin, suggesting the involvement of proteasomal degradation (Fig.