Words similar to kupffer
Example sentences for: kupffer
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Activated Kupffer cells and neutrophils release ROIs and proteases in response to inflammatory cytokines in the liver [ 21].
Objects were assigned 'rankings' of their probability of belonging to a given class plotted against spatial relationships, allowing for quick identification and correction of errors; for example, an object classified as a Kupffer nucleus (other nucleus) should not exist outside of a certain proximity to a sinusoid.
It has been suggested that, after iv administration, low dose intravenous adenoviral vectors are taken up by Kupffer cells and degraded quickly within a few hours [ 1 9 ] whereas higher doses saturate these cells and the surplus productively transduce hepatocytes.
VEGF mRNA peaks at 72 hours after CCl 4 treatment in Kupffer cells, whereas it peaks at 7 days in hepatocytes, well after necrosis has resolved and when vascular and sinusoidal endothelial cells are reappearing in the tissue [ 23 31 ] . Correlation of VEGF isoforms with specific tissue metrics suggests they have different roles in the regeneration and revascularization of severely damaged areas of the treated livers.
This is an ADAM10-homolog known to be a tumor necrosis factor-α (TNFα) convertase [ 21 ] , TNFα produced by Kupffer cells in the liver stimulates production of TNFα, a mitogen for hepatocytes helping to generate new cells needed to rebuild damaged areas of the liver [ 22 ] . Kupffer cells have a significant role as mediators of acute inflammation after CCl 4 treatment; however, they also produce factors that can cause secondary injury in the liver through fibrogenic responses.
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