Words similar to kupffer
Example sentences for: kupffer
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VEGF mRNA peaks at 72 hours after CCl 4 treatment in Kupffer cells, whereas it peaks at 7 days in hepatocytes, well after necrosis has resolved and when vascular and sinusoidal endothelial cells are reappearing in the tissue [ 23 31 ] . Correlation of VEGF isoforms with specific tissue metrics suggests they have different roles in the regeneration and revascularization of severely damaged areas of the treated livers.
This is an ADAM10-homolog known to be a tumor necrosis factor-α (TNFα) convertase [ 21 ] , TNFα produced by Kupffer cells in the liver stimulates production of TNFα, a mitogen for hepatocytes helping to generate new cells needed to rebuild damaged areas of the liver [ 22 ] . Kupffer cells have a significant role as mediators of acute inflammation after CCl 4 treatment; however, they also produce factors that can cause secondary injury in the liver through fibrogenic responses.
Activated Kupffer cells and neutrophils release ROIs and proteases in response to inflammatory cytokines in the liver [ 21].
Objects were assigned 'rankings' of their probability of belonging to a given class plotted against spatial relationships, allowing for quick identification and correction of errors; for example, an object classified as a Kupffer nucleus (other nucleus) should not exist outside of a certain proximity to a sinusoid.
It has been suggested that, after iv administration, low dose intravenous adenoviral vectors are taken up by Kupffer cells and degraded quickly within a few hours [ 1 9 ] whereas higher doses saturate these cells and the surplus productively transduce hepatocytes.
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