Words similar to krc

Example sentences for: krc

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The fifty-three KRC/ZAS-N-selected sequences (ZAS-N dataset) and 49 KRC/ZAS-C-selected sequences (ZAS-C dataset) were first analyzed by the Motif Expectation Maximum for Motif Elicitation (MEME) computer program.
As the most abundant RSS-binding species detected in thymus [ 50 ] , it is intriguing to propose a role for KRC in regulation of the V(D)J recombination process.
KRC was independently cloned due to its ability to bind the RSS [ 14 ] and the κB [ 4 ] motifs.
Based on the results here, we hypothesize that each DNA binding domain of KRC binds to pentameric TG-rich sequences.
With respect to the heptamer (canonical sequence: CACAGTG), the CAC sequence bordering the recombination site is the most conserved segment of the sequence [ 32 ] , and mutation of these nucleotides has been found to decrease V(D)J joining in transfection assays using recombination substrates [ 40 ] . Because the sequence of the canonical RSS heptamer is palindrome, we speculate that the TGTG sequence may be sufficient for KRC/ZAS-C binding.