Words similar to krc

Example sentences for: krc

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In the subsequent rounds, the yield of the DNA-protein complexes increased, suggesting successful enrichment of KRC binding sites in the recovered oligonucleotides during the selection procedures.
The crystal structure of the zinc finger pairs of tramtrack-DNA duplex revealed that the two fingers together contacted 5 base-pairs "A 1G 2G 3A 4T 5" in the major groove of DNA: The first finger interacts with A 1G 2G 3while the second finger interacts with G 3A 4T 5 [ 33 ] . By inference, each zinc finger pair of KRC might also bind to a pentamer.
Similarly, two closely migrating DNA-protein complexes were clearly seen for KRC/ZAS-C at rounds three through five (labeled C, Fig.
We had previously shown by methylation interference analysis that KRC/ZAS-C bound specifically to the sequence TGTGG within the context of the canonical RSS heptamer plus the immediately flanking guanine [ 14 ] . Because the pentamer motif for KRC/ZAS-C predicted by MEME completely matched with the empirical results, we conclude that the two pentameric motifs discovered by MEME are likely authentic binding sites for KRC/ZAS-N as well.
It is possible that two KRC molecules may be needed to interact with an RSS nonamer: one protein whose ZAS-N domains may bind to the 5'-half of an RSS nonamer while a second protein's ZAS-N domain may bind to the 3'-half of an RSS.