Example sentences for: kras

How can you use “kras” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To evaluate the possibility that secondary KRAS mutations confer acquired resistance to these drugs, we performed mutational profiling of KRAS2 exon 2 from tumor specimens from patients 1 to 3, as well as the three additional patients lacking evidence of the T790M mutation.

  • Here, we show that mutations in KRAS are associated with primary resistance to single-agent gefitinib or erlotinib.

  • Some 15%–30% of lung adenocarcinomas contain activating mutations in the RAS family member KRAS . These mutations are most frequently found in codons 12 and 13 in exon 2 [5,6], and may be associated with unfavorable outcomes [7].

  • We systematically evaluated 60 lung adenocarcinomas from patients with known responses to either of these drugs for the presence of mutations in EGFR (exons 18 through 21) and KRAS2 (exon 2).

  • Mutational Analyses of EGFR and KRAS in Lung Tumors


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