Example sentences for: knock-out

How can you use “knock-out” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, similar levels of p21 mRNA in the livers of wild-type and homozygous C/EBPα knock-out mice [ 22 ] argue against a physiologically significant contribution of C/EBPα to p21 gene transcription in the liver.

  • Supporting evidence for the involvement of IGF-II in the proliferative effect resulting from loss of M6P/IGF2R function comes from studies of M6P/IGF2R knock-out mice.

  • In order to confirm the yeast database entry indicating that the MDN1 (YLR106C) gene is essential for viability in yeast, we performed tetrad analysis of the heterozygous midasin knock-out strain CMEY072(HE) (Mat a/α ura3-52/ura3-52 his3D1/his3D1 leu2-3_112/leu2-3_112 trp1-289/trp1-289; MDN1(4,14727)::kanMX4/MDN1) obtained from EuroScarf.

  • Hence the signaling mechanism, like that reported in normal myotubes and dysgenic myotubes expressing wt-α 1S , was Ca 2+entry independent [ 29 ] . We also expressed fs-α 1S in cultured myotubes from two available gene knock-out (KO) mice, lacking the endogenous β1a isoform of the skeletal muscle DHPR [ 30 ] and lacking RyR1 [ 31 ] . As shown in Fig.

  • Dazl1 knock-out mice have already been generated and studied [ 6 ] . The spermatogenic defect in the male becomes apparent only after day 7 post partum when the germ cells are committing to meiosis (H.


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