Example sentences for: kinases

How can you use “kinases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Data suggest that membrane association of Itk and Btk requires the interaction of their PH domains with products of PI3K, thereby facilitating phosphorylation by Src family kinases [ 27, 28].

  • NFAT nuclear localization is regulated by the action of a specific phosphatase and a number of kinases [ 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21].

  • Polo-like kinases phosphorylated and disrupted Net1N/Cdc14 complex, raising the question whether disassembly of the complex in vitro required phosphorylation of Net1N or Cdc14 or both.

  • The two kinases can be immunoprecipitated when co-expressed.

  • One of the major cellular serine/threonine protein phosphatases is protein phosphatase type 1 (PP1) [ 1 ] . An abundant enzyme expressed in all cells, complex regulation of PP1 is thought to be essential for proper temporal and spatial regulation of PP1 catalytic activity towards individual substrates [ 2 ] . Three different isotypes of the catalytic subunit, designated PP1α, PP1δ, and PP1γ1, are expressed in many different cell types [ 3 ] . Studies employing many eukaryotic systems all point to a crucial role for PP1 activity in controlling cell cycle progression, and an absolute requirement of this activity for mitotic exit [ 4 5 6 7 ] . There is also evidence to suggest that phosphorylation of PP1 and its associated proteins by the cyclin-dependent kinases may regulate PP1 activity in a cell cycle stage-dependent manner [ 8 9 10 ] . Hence, current efforts are directed towards identification of cell cycle-dependent substrates for PP1, and how regulation of PP1 activity towards these substrates controls the cell division cycle.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast