Words similar to kidneys
Example sentences for: kidneys
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In conclusion, kidneys of S rats have been shown to be very sensitive to hypertensive injury, which is mediated at least in part by the apoptotic mechanism controlled by Fas.
In addition, SD animals were healthy, the intake of either diet was similar, and they demonstrated no renal abnormalities [ 27 28 29 ] . In the present study, by day 21 the kidneys of S rats demonstrated significant vascular, glomerular and tubulo-interstitial injury.
Quantification analysis comparing the four groups of rats in the study showed that expression of Fas in glomerular and tubular cells was greatest (P < 0.05) in kidneys of S rats exposed to the 8.0% NaCl diet for 7 and 21 days (Fig.
Cyclin D 1 is characterized as the major D-type cyclin controlling G 1 -phase progression in kidney cells, both during normal and abnormal proliferation [ 22 23 ] . To determine whether cyclin D 1 may be active in promoting G 1 → S progression in kidneys expressing HIV-1 genes, we utilized a well-characterized HIV-1 transgenic mouse model (Tg26) of HIVAN [ 11 12 13 ] . Secondary to renal expression of the HIV-1 NL4-3 Δ gag-pol proviral transgene, adolescent Tg26 transgenics develop a progressive, proliferative renal disease marked by podocyte and tubular epithelial hyperplasia that is indistinguishable both clinically and histopathologically from human HIVAN.
The mouse anti-rat LHR monoclonal antibody (mAb), clone 3B5, was developed against purified rat LHR [ 21 ] . The antibody showed immunoreactivity with rat granulosa cells of mature (preovulatory) follicles, ovarian thecal and interstitial cells, granulosa-lutein cells of developing, mature and regressing CL, and with testicular Leydig cells, and no reactivity with rat kidneys [ 22 ] . During the last ten years, affinity purified 3B5 antibody has been used in several immunohistochemical studies [ 23 24 25 26 ] . To our knowledge, however, no analysis of the 3B5 antibody by western blot has been reported.
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