Words similar to kidney-recovered
Example sentences for: kidney-recovered
How can you use “kidney-recovered” in a sentence? Here are some example sentences to help you improve your vocabulary:
Analysis of the chromosomal DNA of the sagA/pelmutant and kidney-recovered variants
Previous studies from our laboratory have consistently demonstrated loss of the SpeB phenotype in S. pyogenes isolates injected in a skin air sac and recovered from the organs of lethally infected mice [ 10 16 ] . This selection was not associated with loss of β-hemolysis but was associated with over-expression of M and M-related proteins, which in turn are predictive of the invasive potential of the organism in a skin infection model [ 16 ] . Based on the phenotypic characteristics of the kidney-recovered variant (β-hemolytic positive, M and M-related protein positive and SpeB negative) we predicted that this variant would be as virulent or more virulent than the wild type organism in the mouse skin infection model.
The results present in figure 5indicate that the kidney-recovered variant was significantly more virulent than the sagA/pel mutant from which it was originally selected (p = 0.018) despite not secreting SpeB or SK in culture (see Table 2).
Northern blot and primer extension analysis confirmed that the sagA/pel gene was transcribed in the β-hemolytic kidney-recovered variant, while sagA/pel message was not seen in the parental β-hemolysis negative sagA/pel mutant.
In this study we have analyzed a representative β-hemolytic positive kidney-recovered variant.
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