Words similar to jra
Example sentences for: jra
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Children with pauciarticular-onset JRA were also significantly more likely to have anti-DEK antibodies than were children with polyarticular-onset or systemic-onset JRA or other rheumatic diseases.
Among children with pauciarticular JRA, DEK autoantibodies were significantly more common in those with JRA-associated uveitis than in those without eye disease [ 8 9 ] . DEK reactivity was also found to be strongly associated with onset of any JRA subtype before age 6 years [ 8 ] .
AS = ankylosing spondylitis; B27 = histocompatibility antigen B27; CREST = calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia; E 2 = estradiol-17β JRA = juvenile rheumatoid arthritis; RA = rheumatoid arthritis; RAD = rheumatic/autoimmune disease; SLE = systemic lupus erythematosus.
The DQA1*0501 allele is strongly associated with early-onset pauciarticular JRA in Northern European populations [ 23 24 ] and with increased risk for juvenile dermatomyositis [ 25 ] and Sjögren's syndrome with high autoantibody production [ 26 27 ] . In our proposed model, aberrant class II MHC regulation could result from altered DEK binding and/or interaction with NF-Y, and aberrant class II expression may alter or enhance reactivity against DEK-derived or other self peptides.
Of these, four had B27 + AS, two had SLE (in one case associated with anti-phospholipid antibodies), one had JRA, and one had juvenile dermatomyositis (Tables 1and 2).
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