Words similar to iκbα

Example sentences for: iκbα

How can you use “iκbα” in a sentence? Here are some example sentences to help you improve your vocabulary:

TNF rapidly induces phosphorylation of IκBα, which normally peaks at 5-10 min, followed by proteasome-dependent degradation (10-20 min) [ 10 24 ] . IκBα degradation and NF-κB activation occurred, as determined 20 min after exposure of control and Hyal-1 cells to TNF.
However, there was an extended period of TNF-mediated IκBα degradation and NF-κB activation in Hyal-2 cells, ranging from 20-60 min.
Next, the effect of TNF-mediated IκBα degradation and NF-κB activation was examined in both Hyal-1 and Hyal-2 cells.
IκBα degradation and NF-κB activation (or NF-κB nuclear translocation) were observed at 20 to 60 min in Hyal-2 cells post TNF stimulation, but at the 20 min time point in both control and Hyal-1 cells (Fig.
IκBα is a physiological inhibitor of NF-κB activation; IκBα complexes with NF-κB and prevents its translocation to the nucleus [ 10 24 ] . NF-κB activation is believed to induce antiapoptotic proteins to block cell death [ 8 ] . However, in several studies activated NF-κB cannot protect cells from apoptosis [ 8 ] . Also, NF-κB appears to be essential in the p53-mediated apoptosis in tested cell lines [ 25 ] .