Example sentences for: iκb
How can you use “iκb” in a sentence? Here are some example sentences to help you improve your vocabulary:
Exposure of cells to stimuli of NF-κB induces the rapid phosphorylation and subsequent degradation of IκB proteins.
In most cell types, the NF-κB p50/p65 heterodimer is maintained as an inactive form in the cytoplasm bound to the inhibitory protein IκB.
In that report, NO was found to induce IκB synthesis through activation of its promoter, therefore, increased IkB-a might also contribute to NF-kB inhibition . Several other possible pathways, e.g. p38, p42/44 MAPK and transcription factors, e.g.
Activation of NFκB involves the increased phosphorylation and proteolytic degradation of IκB.
BSA = Bovine serum albumin; CSC = cigarette smoke condensate; ERK = extracellular signal-regulated kinase; GM-CSF = granulocyte-macrophage colony-stimulating factor; HBE = human bronchial epithelial cell; IL = interleukin; IκB = inhibitor of NFκB; MAPK = mitogen-activated protein kinase; MEK-1 = MAPK kinase; NFκB = nuclear factor-kappa B; NHBE = normal human bronchial epithelial cell; PBS = phosphate-buffered saline; PDTC = pyrrolidine dithiocarbamate; RT-PCR = reverse transcriptase-polymerase chain reaction; sICAM = soluble intercellular adhesion molecule; TNF = tumour necrosis factor; TUNEL = deoxynucleotidyl transferase-mediated dUTP nick end labeling