Example sentences for: iκb
How can you use “iκb” in a sentence? Here are some example sentences to help you improve your vocabulary:
Substrates of AKT include glycogen synthase kinase 3 (GSK3), p70/S6 kinase, BAD, Caspase 9, 4E-BP1, IκB kinase α and members of the Forkhead transcription family [reviewed in ref.
Exposure of cells to stimuli of NF-κB induces the rapid phosphorylation and subsequent degradation of IκB proteins.
CDDO = 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; DMEM = Dulbecco's modified Eagle's medium; GAPDH = glyceraldehyde-3-phosphate dehydrogenase; IκB = inhibitor of NF-κB; IL = interleukin; MMP = matrix metalloproteinase; OA = osteoarthritis; RA = rheumatoid arthritis; RT-PCR = reverse-transcriptase polymerase chain reaction; TNF-α = tumor necrosis factor-α.
In most cell types, the NF-κB p50/p65 heterodimer is maintained as an inactive form in the cytoplasm bound to the inhibitory protein IκB.
Treatment of cells with increasing concentrations of CSC resulted in an initial rise in phosphorylated IκB levels followed by a decrease (Fig.