Example sentences for: iκb
How can you use “iκb” in a sentence? Here are some example sentences to help you improve your vocabulary:
Treatment of cells with increasing concentrations of CSC resulted in an initial rise in phosphorylated IκB levels followed by a decrease (Fig.
NHBEs exposed to CSC also showed an increase in nuclear staining of phosphorylated IκB as detected by immunocytochemical staining using an antibody to phosphorylated IκB (Fig.
The Toll-like receptor family [ 49], which has evolutionary roots throughout invertebrate metazoans for pattern-based recognition of bacterial and fungal cell-surface components [ 50], activate NFκB through convergent pathways involving the IL-1 receptor-associated kinase (IRAK), the adaptor protein MyD88, TRAF6, NFκB-inducing kinase (NIK), and IκB kinase (Iκk) [ 51].
In that report, NO was found to induce IκB synthesis through activation of its promoter, therefore, increased IkB-a might also contribute to NF-kB inhibition . Several other possible pathways, e.g. p38, p42/44 MAPK and transcription factors, e.g.
Both aspirin (via IκB kinase) and rosiglitazone (via PPARγ) inhibit NF-κB [31,32], which is activated by LPS.
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