Example sentences for: iκb

How can you use “iκb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Among the most highly induced were the genes encoding NFκB1, RelB, IκB-alpha (the inhibitor of NFκB1), IκKε (IκB kinase-epsilon), and NFκB-inducing kinase or Map-3-kinase-14 (NIK, MAP3K14).

  • To determine whether upregulation of cytokine production by CSC involved activation of NFκB, we examined CSC-treated epithelial cells for phosphorylation of the inhibitor of NFκB (IκB).

  • We have recently reported the role of the inhibitor of NF-κB (IκB) family member Bcl-3 in IL-1-induced MMP-1 expression [ 24 ] . Here we show that overexpression of Bcl-3 can partly abrogate CDDO's inhibitory effects on MMP-1 in SW-1353 cells, suggesting that Bcl-3 might be a target for CDDO.

  • In the same time-course experiment, we assayed for the presence of Bcl-3, an IκB family member that we have previously shown to have a role in MMP-1 expression.

  • For example, transcription factors belonging to the NF-κB family are activated by a wide variety of cellular signaling events, and several known NF-κB target genes ( A1, A20, c-IAP1, c-IAP2, IκB alpha, IκB epsilon, CD54, IL-6, IL-8, TNF-α, IRF-4 ) were found to have unstable mRNAs (Figure 4d).


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