Example sentences for: ischemia

How can you use “ischemia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It has recently been reported that transient forebrain ischemia leads to the expression of the inotropic AMPA glutamate receptor GluR4 subunit in vivo [ 24 ] in rat neonatal microglia.

  • In cases where the CEC had identified a MI and the site investigators had not, one-third of those identified were MIs defined by enzyme elevations without clinical or ECG evidence of ischemia or infarction (Table 2).

  • in vivo following transient forebrain ischemia [ 24 ] and also in vitro by rat neonatal microglia [ 41 ] . Because it is well established that AMPA glutamate receptors bind domoic acid with high affinity in the nanomolar range [ 25 ] , we investigated the presence of GluR4 in rat neonatal microglia used in our in vitro experiments by a dual-labeling indirect immunofluorescence technique.

  • An accumulation of 4-HNE-conjugated protein has been detected in lesions of aging-related diseases, including Parkinson's disease [ 53 ] and Alzheimer's disease [ 54 ] . It also accumulates in the affected neuronal tissues of experimental animals experiencing brain ischemia [ 55 56 ] and traumatic spinal cord injury [ 57 ] . 4-HNE can impair synaptosomal membrane proteins, glutamate transport and importantly, mitochondrial functions [ 58 59 ] . Evidence indicates that 4-HNE increases neuronal susceptibility to oxidative stress [ 60 ] and serves as a mediator of oxidative stress that leads to neuronal apoptosis [ 61 ] . As indicated in the Introduction, 4-HNE has been implicated in some ocular pathological conditions [ 19 20 ] .

  • Most patients experience neck, facial, and head pain ipsilateral to the lesion because of ischemia or stretching of the trigeminal pain fibers surrounding the carotid arteries [2].


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