Example sentences for: irreversibly

How can you use “irreversibly” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The paper said, "Netanyahu came into office as leader of the opposition to the Oslo Accords; he is leaving having brought the Likud solidly and irreversibly into the Oslo camp.

  • IFN-γ potently and irreversibly inhibits RANKL-induced osteoclastogenesis

  • Our studies provide first systematic data that cells should be kept in 4% PFA for at least 60 min at room temperature or for 20 min at 37°C to irreversibly crosslink most of the polypeptides (Figure 6).

  • For this reason, it is preferable that microbicides irreversibly inactivate the virus upon the first compound/HIV-1 encounter in the vaginal environment, i.e. microbicides should have direct virucidal activity.

  • In a separate study, we have shown that Az and HsN3 play targeting roles in the proteasomal degradation of Smad1 upon the activation of BMP type I receptors [ 39 ] . The observed proteasomal degradation of Smad1 upon the activation of BMP signaling could simply serve to irreversibly terminate Smad1-mediated signaling pathways of BMPs.


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