Example sentences for: irreversible

How can you use “irreversible” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Among the two, fraction CM-IV-6A was found to induce progressive, irreversible flaccid paralysis at the dose of 1 μg/100 mg per larva of Heliothis virescens.

  • Ciliates employ a strategy of irreversible genome alterations to generate the MAC, a specialized gene-expression organelle.

  • This alanine to serine mutation in the C-terminal region of α i1 (A326S) and α s (A366S) has been shown to greatly accelerate GDP release, to accelerate irreversible inactivation in vitro , and to cause rapid turnover of the α subunit in cultured cells [ 9 10 ] . Thus, if the observed intracellular localization of sα i2 is caused by instability of the protein due to disruptions at its C-terminus, then it follows that α i2 A327S should show a similar pattern of localization.

  • βγ prevents irreversible inactivation of α i1 , when measured in vitro at 37°C, and slows the inactivation of α i1 A326S [ 10 ] . Thus, βγ may stabilize sα i2 and α i2 A327S allowing βγ-dependent [ 25 26 27 28 29 ] PM localization.

  • Deubiquitinases, such as Rpn11, serve as proofreading devices for reversal of fortune at various stages of the process, right up to the final step before irreversible degradation by the proteasome.


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