Words similar to irreversible

Example sentences for: irreversible

How can you use “irreversible” in a sentence? Here are some example sentences to help you improve your vocabulary:

In ischemic stroke, the most common type, a profound disturbance of focal cerebral blood flow leads to irreversible parenchymal injury.
The helix-bundles were also induced by heating HIV-1 virus particles at 60°C, in agreement with the irreversible induction of the fusogenic conformation in influenza virus hemagglutinin by heat [ 58 59 ]
The rapid and irreversible effects of IFN-γ on osteoclast inhibition indicate a dominant effect of this cytokine over RANKL via induction of monocyte differentiation toward the activated macrophage fate, as opposed to the osteoclast fate, when concomitantly administered.
These effects were irreversible and not caused by inhibition of proximal signaling at the level of STAT1 or TRAF6, suggesting that resistance to IFN-γ is caused by a complex differentiation program specifying the osteoclast fate.
By glutathionylating a single cysteinyl residue, the protein is protected from further oxidation of that cysteinyl residue to the irreversible sulfinic and sulfonic acid forms.