Example sentences for: irreversible

How can you use “irreversible” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Among the two, fraction CM-IV-6A was found to induce progressive, irreversible flaccid paralysis at the dose of 1 μg/100 mg per larva of Heliothis virescens.

  • Such deletions are apparently irreversible in obligate mutualists, which lack recombination functions and genetic elements, such as prophages, transposons, and repetitive DNA that typically mediate gene acquisition.

  • Soluble CAP at neutral pH was shown to bind strongly to the coreceptor binding sites on gp120 of both X4 and R5 viruses [ 36 ] and to elicit the formation of gp41 six-helix bundles, the hallmark of irreversible virus inactivation [ 37 ] . Thus, HIV-1 exposed to CAP at sufficient concentrations is rendered noninfectious, and continued presence of CAP is not required to maintain lack of infectivity.

  • The loss of cytochrome c causes a break in the electron transfer chain resulting in the production of reactive oxygen species [ 31 ] . Reactive oxygen species are known to cause the oxidation and loss of function of many lipids including cardiolipin [ 20 ] . Finally, caspases activated downstream of cytochrome c release have been implicated in mitochondrial damage [ 29 ] . It appears likely that the cumulative damage of these agents could lead to the irreversible loss of mitochondrial membrane integrity and structure.

  • Furthermore reversible inhibitors are less likely to cause enzyme malfunction [ 8 ] than irreversible ones.


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