Example sentences for: irf-

How can you use “irf-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, transcription factors belonging to the NF-κB family are activated by a wide variety of cellular signaling events, and several known NF-κB target genes ( A1, A20, c-IAP1, c-IAP2, IκB alpha, IκB epsilon, CD54, IL-6, IL-8, TNF-α, IRF-4 ) were found to have unstable mRNAs (Figure 4d).

  • Other inducible transcription factors with labile mRNAs have more lymphocyte-specific functions, such as IRF-4, a factor that is required for lymphocyte activation but is not required in other lineages [ 33].

  • IRF-1 has been reported to be upregulated by TNFα during sepsis [ 35 ] . The correlation between this cytokine and area % vacuoles but not with vacuoles/mm 2shows the dynamic balance between the primary response to injury and tissue proliferation and repair.

  • In contrast, area % vacuoles was linked to expression of interferon regulatory factor 1 (IRF-1; M34253).

  • Different functional subsets of genes were identified that included those for several chemokines (GRO-1, MIG, MCP-1, MCP-3, MIP1-α, MIP-β, PARC, IL-8), cytokine receptors (C-CR-1, IL-R, IL-1R antagonist, IL-2Rβ, transforming growth factor-β receptor (TGFβR), IFNγR α chain), adhesion molecules associated with mononuclear cell migration (CD62L, VCAM-1, CD64, CD29), cytotoxic proteins in granules produced by activated monocytes (grancalcin and calgranulin) and several genes associated with IFN-γ activity, such as HLA class II molecules and IFN-regulatory or responsive genes such as those for MxA, MxB and IRF-1.

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