Example sentences for: ires

How can you use “ires” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A mechanism of translation initiation utilizing an internal ribosome entry site (IRES [ 63]) appears a better explanation for these cases.

  • Association of Screening Set STRPs with interspersed repeat elements (IREs) is shown in Table 5. STRPs were considered to be associated with IREs if the IRE fell in the 50 bp flanking the STR on either side (total of 100 bp of flanking sequence).

  • Here integration of the transgene at the gene-trap locus was again mediated by Cre recombinase and translation of the transgene was facilitated by an internal ribosomal entry site (IRES) [ 24].

  • Since, the TAR is located at the 5' end of all HIV-1 RNA transcripts and the presence of secondary structure at or near the 5' end of RNAs reduces the accessibility of the 5' cap to eIF4F, it is thought that this feature of HIV-1 mRNAs can inhibit their cap-dependent translation [ 44 45 46 ] . Therefore, a possible function of the HIV-1 gag IRES might be to serve as a mechanism to bypass the structural barriers to cap-dependent translation by recruiting ribosomes easily and directly to the gag ORFs.

  • IRES entirely contained within a translated ORF has been shown in the MMLV gag [ 47 ] , and host mRNA encoding p110 PITSLREand p58 PITSLRE [ 48 ] . Along these lines, cap-dependent translation may be cell cycle regulated, especially when cells are arrested at the G2 phase of the cell cycle, where the cap-dependent translation of most cellular host cell mRNAs is inhibited [ 49 50 51 ] .


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