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Example sentences for: ipcs

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Collectively, these experiments confirm that IPCs transcribe and translate insulin, and rule out that insulin measured in IPCs is derived from medium, as shown in another system [39].
Immunostaining with specific antibodies revealed proinsulin and C-peptide, an internal portion of the proinsulin translation product, in the cytoplasm of all insulin + cells (see Figure 4D–4G and 4O), supporting our conclusion that insulin protein was produced in stage 4 IPCs.
To test whether IPCs respond appropriately to glucose stimulation, we measured insulin release in static batch in vitro assays.
Glucokinase and glucose transporters like Glut-2 are essential regulators of glucose responses in pancreatic β-cells, and expression of these regulators in stage 4 insulin + cells (see Figures 1C, 4M, and 4N) suggested that IPCs could sense and respond to glucose.
IPCs Are Glucose Responsive