Example sentences for: intimal

How can you use “intimal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Atherosclerosis begins as a lipid and inflammatory cell deposition in the intimal subendothelial space, which expands outward, with only a slight inward intrusion on the lumen.

  • Verhoeff-van Gieson staining indicated the focal destruction of aortic elastic fibrils in addition to intimal thickening (Fig.

  • The number of CCL3 and CCL5 positive intimal cells did not differ between RA and non-RA tissue.

  • The normal intima of the synovium is one to two cells thick and consists mainly of macrophage-like and fibroblast-like cells [ 3 ] . In inflammation, macrophages make a large contribution to intimal thickening, where these cells increase in number and proportion [ 3 ] . Evidence indicates that intimal macrophages arrive via the circulation as monocytes [ 4 ] , and it is proposed that increased numbers of intimal macrophages in RA are largely attributed to enhanced monocyte recruitment from blood vessels in the synovium [ 1 5 ] . Neutrophils are also recruited in RA and can be found in abundance in synovial fluid, yet they occur in relatively low numbers in the synovium [ 5 ] . In synovial fluid their number can reach 10 6per joint, particularly during an active phase of the disease [ 6 ] . Neutrophils occur at the pannus-cartilage junction [ 7 ] and it is presumed that these cells reach the joint cavity by migrating from the blood vessels in the synovium, following a chemotactic gradient.

  • In two of these individuals a minority of synovial samples also showed microscopically normal regions with minimal infiltration of inflammatory cells and an intimal layer of normal thickness (one to two cells thick).


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