Example sentences for: intergenically

How can you use “intergenically” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We sought to determine the genomic structure of YL-1 when we discovered that it lies next to and intergenically splices into TMOD4 (see below).

  • During the course of this study, the gene mutated in LGMD1B was identified as Lamin A/C [ 24 ] . Our investigation, however, revealed that an unrelated gene, YL-1, intergenically spliced into TMOD4 . YL-1 is a putative transformation suppressor gene that localizes to the nucleus and binds to DNA [ 25 26 ] . YL-1 is organized into six exons and produces several alternatively spliced transcripts using both intergenic and cryptic splicing.

  • The human cytochrome P450 2C gene cluster maps to chromosome 10q24 and consists of four genes which are composed of nine exons with conserved exon/intron boundaries, and have been shown to produce intergenic transcripts [ 35 36 37 38 ] . These transcripts have been identified by RT-PCR for both neighboring genes such as CYP2C18 and CYP2C19, as well as CYP2C members separated by another gene, such as CYP2C18 and CYP2C8 [ 37 38 ] . The latter was shown by RT-PCR to include exons from both genes consisting of nine exons and therefore could code for a chimeric CYP2C protein [ 38 ] . Recently, the Translin-associated factor X gene (TRAX) was demonstrated to intergenically splice into Disrupted in schizophrenia gene 1 (DISCI) [ 39 ] . Several intergenic transcripts were described, the majority of which contain intervening non-coding exons that contain multiple stop codons.


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