Example sentences for: insulin-like

How can you use “insulin-like” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The increased life span regulated by the insulin-like signaling pathway in C. elegans is associated with increased resistance to stress, including oxidative stress [ 18, 19, 20, 21].

  • LIF and CNTF stimulate muscle regeneration in vivo [ 62 63 ] , as do other growth factors; such as insulin-like growth factor [ 64 65 ] . The power of LIF to regenerate muscle is seen in dystrophin null mdx mice, where exogenous LIF regenerates atrophied diaphragm muscle [ 66 ] . LIF induced signaling appears to be essential in muscle development as seen by muscle atrophy in the absence of LIFR on E18.

  • Using this approach, we have successfully identified peptide agonists and antagonists for a number of biologically important molecules including growth hormone receptor, insulin receptor and the insulin-like growth factor receptor [ 2 3 ] .

  • et al . found significantly different baseline expression levels of insulin-like growth factor (IGF) and insulin-like growth factor binding protein (IGFBP) between normal and AIS-derived genital skin fibroblasts, and could not detect changes in transcript levels in response to androgen treatment [ 29 ] . In normal genital fibroblasts, androgen-responsive reporter genes can only be activated by expression of co-transfected AR in the presence of ligand [ 30 ] . Therefore, endogenous AR expression itself may be insufficient in genital skin fibroblasts to elicit a transcriptional response.

  • PIP3: Phosphatidyl-3,4,5-triphosphate; DMEM: Dulbecco's Modified Eagle's Medium; PI-3Kinase: phosphatidylinositol-3-kinase; MAPK: mitogen-activated protein kinase; IGF: insulin-like growth factor; PTEN: phosphatase and tensin homolog deleted from chromosome 10; SOS: son-of-sevenless ras exchange factor; ASK: apoptosis stimulating kinase; FKHR: forkhead related protein; cFLIP: cellular FLICE interacting protein; BSA: bovine serum albumin; TBS: tris buffered saline; PVDF: polyvinylidene difluoride


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