Words similar to insulin-like
Example sentences for: insulin-like
How can you use “insulin-like” in a sentence? Here are some example sentences to help you improve your vocabulary:
CD26 is an ectoenzyme, which delivers a costimulatory signal in T-cells; its expression is upregulated on T-cells in response to mitogenic signals and downregulated through interaction with the insulin-like growth factor II receptor [ 16 ] . The consequence of CD26 loss is unclear; CD26 modulates the action of many molecules including the chemotactic activity of some chemokine important for T-cell migration to skin [ 17 18 ] .
In contrast to the adverse effects of intra-articular adenoviral gene transfer of TGF-β1, we have shown that gene transfer of insulin-like growth factor type 1 to the rabbit knee results in an increase in new matrix synthesis without any adverse effects [ 17 ] .
In this report, we questioned whether the EGFR acts as a surrogate scaffold during ERK activation through the δ-OR, as it appears to do for several other GPCRs [ 7 ] . To act as a surrogate-binding site for complex formation, the literature states that this protein must first become tyrosine-phosphorylated [ 7 ] . Tyrosine phosphorylation of the EGFR is apparent after agonist stimulation of the α 2 -AR (COS-7), β 2 -AR (COS-7), insulin-like growth factor (IGF-1; COS-7), substance P, and the lysophosphatidic acid receptor (LPAR) [ 7 ] . In addition, each of the aforementioned ligands also increases ERK phosphorylation when the proper receptor is expressed in these cell lines.
. daf-2 encodes a receptor that is similar to those for insulin and insulin-like growth factor-1 (IGF-1) in humans; this hormone receptor normally speeds up ageing in worms, but the mutations inhibit its action and enable the organisms to live longer.
Also of interest are genes that are upregulated in both the cancers, including IGFBP3 (insulin-like growth factor binding protein 3), which, interestingly, is thought to have proapoptotic activities [ 14 ] , and GSN (gelsolin), which has a role in cellular motility and acts as both a regulator and effector of apoptosis [ 15 ] . Further xenograft studies of the type presented here could examine the responses of the host tissue to the tumor (using a mouse microarray chip), as well as temporal changes in gene expression within the developing tumor.
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