Words similar to inotropy
Example sentences for: inotropy
How can you use “inotropy” in a sentence? Here are some example sentences to help you improve your vocabulary:
In these studies EMD 57033 resulted in only small increases in myocardial oxygen consumption and this was felt related to the ability of EMD 57033 to increase inotropy without increasing calcium cycling (though intracellular calcium was not directly measured).
In the perfused mouse heart, high perfusate calcium positive inotropy compared to dobutamine results in reduced myofilament calcium responsiveness, decreased energetic efficiency and is dependent in part on protein kinase C activation.
The mechanisms controlling calcium-induced inotropy are probably several fold, and include activation of protein kinase C [ 8 ] , of which several isoforms are calcium dependent.
; 4) to antagonize the effects of protein kinase C, the specific antagonist chelerythrine (ref 30; 10 nM, Calbiochem-Novabiochem Intl, La Jolla, CA) was added to the perfusate when inducing positive inotropy.
The specific protein kinase C inhibitor chelerythrine significantly inhibited high calcium positive inotropy (2.