Words similar to inotropy
Example sentences for: inotropy
How can you use “inotropy” in a sentence? Here are some example sentences to help you improve your vocabulary:
In these studies EMD 57033 resulted in only small increases in myocardial oxygen consumption and this was felt related to the ability of EMD 57033 to increase inotropy without increasing calcium cycling (though intracellular calcium was not directly measured).
To study this we directly measured developed pressures, myocardial oxygen consumption and used a newly developed technique to measure intracellular calcium in perfused mouse hearts with the calcium sensitive fluorescent dye rhod-2 [ 6 7 ] during calcium-induced inotropy and with dobutamine.
; 4) to antagonize the effects of protein kinase C, the specific antagonist chelerythrine (ref 30; 10 nM, Calbiochem-Novabiochem Intl, La Jolla, CA) was added to the perfusate when inducing positive inotropy.
Thus, we predicted that high perfusate calcium positive inotropy would result in lower developed pressures relative to both intracellular calcium and myocardial oxygen consumption compared to dobutamine, and that high perfusate calcium would be associated with evidence of protein kinase C activation, though not dobutamine.
In the present study, we hypothesized that energy consumption during altered inotropy is largely to related calcium handling.