Example sentences for: inotropic

How can you use “inotropic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Prior studies have shown variability in the use of therapeutic modalities (including PACs, ventilator, and intravenous vasoactive and inotropic agents) among ICU patients [ 21 27 ] and different impacts on outcomes and use of hospital resources associated with these treatments [ 16 17 18 28 29 ] . In general, with the exception of the recent trial demonstrating benefit of early goal-directed treatment involving oxygenation (including ventilatory support if necessary) and blood pressure (including intravenous pressors if necessary) [ 30 ] , few data are available that demonstrate that these modalities improve outcomes.

  • The regulation of lumenal diameter in large arteries is accomplished through the maintenance of shear stress along the arterial wall [ 38 50 51 52 53 54 ] . As blood flow through an artery increases, shear is also increased, and the endothelium releases nitric oxide for vasodilation [ 55 ] . Chronically, the arterial wall will remodel to a larger diameter to accommodate the increased flow [ 38 ] . While we did not measure arterial flow through these iron deficient arteries, the enhanced inotropic compensation to iron deficiency, combined with the enlarged aortic diameter, leads us to suspect a flow dependent mechanism for remodeling.

  • Our results suggest that iron deficient, hypertrophic hearts display a hyper-sensitive inotropic, but not chronotropic, response to norepinephrine.

  • Indeed, dopamine's multiple effects (even at low doses) make it the perfect pressor/inotropic agent when such a combination is warranted.

  • It has recently been reported that transient forebrain ischemia leads to the expression of the inotropic AMPA glutamate receptor GluR4 subunit in vivo [ 24 ] in rat neonatal microglia.


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