Example sentences for: inotropic

How can you use “inotropic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Such a patient may well benefit from the combined inotropic, vasopressor, renal vasodilator and diuretic effects of this drug.

  • Prior studies have shown variability in the use of therapeutic modalities (including PACs, ventilator, and intravenous vasoactive and inotropic agents) among ICU patients [ 21 27 ] and different impacts on outcomes and use of hospital resources associated with these treatments [ 16 17 18 28 29 ] . In general, with the exception of the recent trial demonstrating benefit of early goal-directed treatment involving oxygenation (including ventilatory support if necessary) and blood pressure (including intravenous pressors if necessary) [ 30 ] , few data are available that demonstrate that these modalities improve outcomes.

  • The initial increase in circulating norepinephrineis thought to maintain cardiac function through inotropic mechanisms.However, a direct cardiac myocyte toxicity from norepinephrine iswell recognized [ 6 7 ] . Furthermore, pressure-overloadand stretch associated release of angiotensin II has been shownto induce myocyte apoptosis [ 8 9 10 ] .In an elegant paper by Telger et al.

  • It has recently been reported that transient forebrain ischemia leads to the expression of the inotropic AMPA glutamate receptor GluR4 subunit in vivo [ 24 ] in rat neonatal microglia.

  • The regulation of lumenal diameter in large arteries is accomplished through the maintenance of shear stress along the arterial wall [ 38 50 51 52 53 54 ] . As blood flow through an artery increases, shear is also increased, and the endothelium releases nitric oxide for vasodilation [ 55 ] . Chronically, the arterial wall will remodel to a larger diameter to accommodate the increased flow [ 38 ] . While we did not measure arterial flow through these iron deficient arteries, the enhanced inotropic compensation to iron deficiency, combined with the enlarged aortic diameter, leads us to suspect a flow dependent mechanism for remodeling.


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