Words similar to inotropic
Example sentences for: inotropic
How can you use “inotropic” in a sentence? Here are some example sentences to help you improve your vocabulary:
The initial increase in circulating norepinephrineis thought to maintain cardiac function through inotropic mechanisms.However, a direct cardiac myocyte toxicity from norepinephrine iswell recognized [ 6 7 ] . Furthermore, pressure-overloadand stretch associated release of angiotensin II has been shownto induce myocyte apoptosis [ 8 9 10 ] .In an elegant paper by Telger et al.
Our results suggest that iron deficient, hypertrophic hearts display a hyper-sensitive inotropic, but not chronotropic, response to norepinephrine.
Prior studies have shown variability in the use of therapeutic modalities (including PACs, ventilator, and intravenous vasoactive and inotropic agents) among ICU patients [ 21 27 ] and different impacts on outcomes and use of hospital resources associated with these treatments [ 16 17 18 28 29 ] . In general, with the exception of the recent trial demonstrating benefit of early goal-directed treatment involving oxygenation (including ventilatory support if necessary) and blood pressure (including intravenous pressors if necessary) [ 30 ] , few data are available that demonstrate that these modalities improve outcomes.
Such a patient may well benefit from the combined inotropic, vasopressor, renal vasodilator and diuretic effects of this drug.
The regulation of lumenal diameter in large arteries is accomplished through the maintenance of shear stress along the arterial wall [ 38 50 51 52 53 54 ] . As blood flow through an artery increases, shear is also increased, and the endothelium releases nitric oxide for vasodilation [ 55 ] . Chronically, the arterial wall will remodel to a larger diameter to accommodate the increased flow [ 38 ] . While we did not measure arterial flow through these iron deficient arteries, the enhanced inotropic compensation to iron deficiency, combined with the enlarged aortic diameter, leads us to suspect a flow dependent mechanism for remodeling.
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