Words similar to initio
Example sentences for: initio
How can you use “initio” in a sentence? Here are some example sentences to help you improve your vocabulary:
CASP4 demonstrated further improvement in our methodologies in both comparative modelling and ab initio prediction [ 26 ] . Our approaches combine a Monte Carlo procedure, simulated annealing, genetic algorithms, graph theory, and semi-exhaustive searches with move sets consisting of fragments and discrete state models, and scoring functions consisting of all atom-based pairwise functions, hydrophobicity indices, secondary structure preferences, and hydrogen bonding.
Therefore, the consolidation and integration of mainly the transcript information into the genomic consensus assures that our putative gene index is largely based on experimental evidence, rather than ab initio gene prediction.
Analyses of small genomes show that about 30-40% of the proteins within the genome can be modelled by comparative modelling and fold recognition methods [ 27 50 52 ] . An additional 20-30% of the sequences are (or contain) small domains with simple secondary structures that are viable candidates for ab initio structure prediction [ 53 ] . The remaining proteins are usually not amenable to structure prediction and sometimes even structure determination (a significant fraction of the latter are membrane proteins).
Only 249 (2%) of protein-coding gene models were created without an ab initio model, that is, solely on the basis of cDNA or protein homology evidence.
There are three primary categories of methods for predicting protein structure from sequence: comparative modelling, fold recognition, and ab initio prediction.
Loading...