Words similar to inf-γ
Example sentences for: inf-γ
How can you use “inf-γ” in a sentence? Here are some example sentences to help you improve your vocabulary:
In CD8 +T cells from African HIV +patients, stimulated with env peptide, both IFN-γ and TNF-α production were increased over controls [ 52 ] . PBMC from the elderly (almost healthy donors) showed upregulation of TNF-α in unstimulated cultures [ 52 ] . HLA-DR activation of CD8 +CD57 +cells from elderly subjects strongly produced TNF-α [ 48 ] . Lipopolysaccharide-activation of T cells from aged donors induced higher levels of TNF-α than controls in two separate studies [ 53 31 ] . Finally, in HIV +patients receiving HIV type 1 antigen, both INF-γ and TNF-α were significantly increased in memory T cells activated by antigen [ 54 ] .
It was shown that the adenoviral infection of the liver activates the innate immunity with increase NK cells and cytokines production (INF-γ, TNF-α, IL-12, IL-6) [ 11 12 13 14 ] . Further, differences of this activation between mouse strains were associated with variation in adenovirus transgene expression [ 11 13 ] . However it was demonstrated that no activation of the innate immunity and that no difference of transgene expression could be observed before the seventh day after the adenoviral administration [ 13 ] . Furthermore the decrease of transgene expression after activation of the innate immunity following i.v.
Thus there appears to be considerable support for the enhanced presence of TNF-α and INF-γ in the HIV +and the aged states, and for a physiologic role of the CD8 +T cell subset in their production.
INF-γ levels in rat sera were measured by an ELISA kit (BioSource Netherlands, B.V.
However, in such perspective we measured the serum level of INF-γ in both rat strains 2 days after the vector administration and no difference could be observed (60 ± 14 pg / ml in the Wag/Rij rats versus 65 ± 18 pg / ml in the Brown Norway rats).
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