Example sentences for: inducible

How can you use “inducible” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The mouse homologue of one of the candidate biomarkers, LNC2, has been shown to be regulated at the transcriptional level by dexamethasone in murine cells [ 22 ] . However, there is no published evidence that the human LCN2 gene is likewise dexamethasone-inducible, and there is no description of glucocorticoid-responsive elements in the 5' regulatory region of the human LCN2 gene [ 28 ] . Further, preliminary investigation in our laboratory, using in vitro cultures of purified PBMCs from healthy volunteers, indicates that neither the LCN2 gene nor any of the other 3 transcripts is directly inducible by acute treatment with either SU5416 or dexamethasone (data not shown).

  • it has been shown that driving transcription through a centromere via an inducible promoter prevents cohesin from associating and results in chromosome missegregation and cell death [13].

  • Along these lines, it has been shown that RSV activation of chemokine gene promoters involves multiple inducible transcription factors including AP-1 [ 52 53 ] , which is also a redox sensitive transcription factor important in chemokine gene expression [ 28 36 54 ] . AP-1 can also be inhibited by DEX and has been shown to cooperate with NF-κB to mediate RSV induction of IL-8 [ 46 55 ] .

  • One cell line (HG2551a) had an 8% transfection efficiency (constitutive GFP) and 0.25% green cells without Tet and 3.8% with 1 μg/ml Tet (15 fold induction and 45% inducible transfection efficiency vs. constitutive), and was chosen for transfection of GFP-BLM alleles.

  • Stable cell lines containing the mutant proteins are inducible with Tet and show altered localization


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