Example sentences for: inducibility

How can you use “inducibility” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • PMA did not improve IFNg inducibility of MHCII in MSTO-211H and HepG2 cell lines (data not shown).

  • The inducibility of many of these genes is known to be due to transcriptional activation of their promoters.

  • Most frequently, poor MHCII inducibility in response to IFNg has been attributed to alterations in the IFNg signalling pathway and epigenetic silencing of gene expression (reviewed in Ref [ 13 ] ). The cascade of IFNg signalling events leading to transcription activation of MHCII genes has been characterized in great detail (reviewed in Ref [ 30 ] ). Binding of IFNg to its receptor results in JAK-mediated phosphorylation of STAT1 on Tyrosine 701.

  • A substantial percentage of human tumors lose the expression of the retinoblastoma tumor suppressor protein (Rb), important as a necessary condition for IFNg-mediated induction of MHCII [ 21 ] . Therefore, we wished to determine whether the poor IFNg inducibility of MHCII in LS1034, MSTO-211H and HepG2 cell lines could be explained by the loss of Rb.

  • Bryostatin 1 rescues IFNg inducibility of MHCII in LS1034 colon carcinoma cells


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