Words similar to inducibility
Example sentences for: inducibility
How can you use “inducibility” in a sentence? Here are some example sentences to help you improve your vocabulary:
We next attempted to restore IFNg inducibility of MHCII in poorly responding tumor cell lines by adding PKC agonist PMA into culture medium containing variable concentrations of IFNg.
It was reported that some agents, e.g. histone deacetylase inhibitors [ 14 ] or DNA methylation inhibitors [ 15 ] , can rescue the IFNg inducibility of MHCII in cultured tumor cells.
PMA did not improve IFNg inducibility of MHCII in MSTO-211H and HepG2 cell lines (data not shown).
Another reported mechanism of IFNg resistance in tumor cells is associated with down-regulation of IFNg-receptors [ 38 ] . The relevance of this mechanism to MHCII inducibility was recently supported by the evidence that PMA is able to enhance IFNg-dependent MHCII expression in THP-1 human leukemia cells through the up-regulation of IFNg receptors [ 19 ] . In our experiments, however, the incubation of LS1034 cells with PMA and ethanol did not lead to any changes in IFNgR expression as determined by flow cytometry (Figure 4).
Bryostatin 1 rescues IFNg inducibility of MHCII in LS1034 colon carcinoma cells