Example sentences for: indomethacin

How can you use “indomethacin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The NSAID sulindac has been shown to cause regression of colorectal adenomas of patients with hereditary forms of polyposis (Familial Adenomatous Polyposis (FAP) and Gardner's Syndrome) [ 17 18 19 ] and in sporadic colorectal adenomas [ 20 ] . In addition, case reports have demonstrated that indomethacin and sulindac were effective co-therapy agents in the treatment of desmoid tumours [ 21 22 ] . Finally, the inclusion either of indomethacin, naproxen or sulindac in the chemotherapy regiment of gastric carcinoma patients resulted in a significant increase in survival; 30 months versus 6 months when NSAIDs included in treatment regime [ 22 ] .

  • In co-cultures, indomethacin resulted in a marked increase of conversion of MMP-9 from the 92 kDa to the 83 kDa form, most readily observed in the absence of NE, where conversion was minimal (Fig.

  • Although some effect of indomethacin on cell growth rate was observed, there was no sign of macroscopic foci (data not shown).

  • Neither indomethacin nor PGE had an effect on MMP-3 on fibroblasts or monocytes cultured alone.

  • While 15d-PGJ 2 is considered to be a PPARγ agonist, indomethacin and ibuprofen can activate both PPARγ and PPARα [ 27 ] . The following experiment was conducted to determine if a pure PPARα agonist, WY14643, could modulate the 25-OH-cholesterol induced cytotoxicity.


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