Example sentences for: indoleamine

How can you use “indoleamine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 13, 14] and confirmed by others [ 15, 16], IFN-γ acts by inducing indoleamine 2,3-dioxygenase, a host enzyme that converts L-tryptophan to L-formylkynurenine.

  • It has been generally observed that in murine systems indoleamine dioxygenase has not been induced by IFN-γ under the same experimental conditions that readily induce synthesis of the enzyme in human systems.

  • Starvation for host-derived L-tryptophan, which is initiated by induction of indoleamine dioxygenase by IFN-γ, undoubtedly triggers derepression of the entire tryptophan operon, including the genes encoding PRPP synthase and kynureninase.

  • Many individual factors could influence the balance, including differential sensitivities of NO synthase to inhibition by 3-hydroxyanthranilate or of indoleamine dioxygenase to inhibition by nitric oxide.

  • It therefore undermines the host's ability to deplete tryptophan through induction of indoleamine dioxygenase.


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