Example sentences for: indoleamine

How can you use “indoleamine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Starvation for host-derived L-tryptophan, which is initiated by induction of indoleamine dioxygenase by IFN-γ, undoubtedly triggers derepression of the entire tryptophan operon, including the genes encoding PRPP synthase and kynureninase.

  • The initial step is rate limiting and is catalyzed by either of two enzymes: indoleamine 2,3-dioxygenase or tryptophan 2,3-dioxygenase.

  • Under conditions in which there is induction of both indoleamine dioxygenase and NO synthase, an interplay of potential cross-pathway inhibitions are set in motion as illustrated in Figure 2. Nitric oxide inhibits indoleamine dioxygenase [ 41].

  • Many individual factors could influence the balance, including differential sensitivities of NO synthase to inhibition by 3-hydroxyanthranilate or of indoleamine dioxygenase to inhibition by nitric oxide.

  • In the case of C. muridarum, the mechanism does not necessarily involve blocking the induction of indoleamine dioxygenase and thereby preventing depletion of host tryptophan, in view of some experimental work with the MoPn/mouse model system.


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