Example sentences for: implicated

How can you use “implicated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Proteases such as MMP-9 [ 9 ] , which have been implicated in sublethal and lethal neuronal and glial injury in vivo in " ...central nervous system diseases.

  • Unless you're extraordinarily lucky, the outcome of making either choice will leave you morally implicated in some dead bodies (with larger raw numbers making up for lack of American citizenship in the case of a "no").

  • While our study suggests that SKP2 is an important player in p27 regulation in prostate cancer cells, recent studies have also implicated another protein, CSN5/JAB1, in p27 regulation [ 54 55 ] . CSN5 is a subunit of the COP9/signalosome (CSN) complex [ 56 57 58 59 ] , but also forms distinct complexes apparently lacking CSN subunits [ 55 60 61 62 ] . Overexpression of CSN5 in NIH3T3 cells causes p27 export from the nucleus and ectopic degradation [ 54 ] . Notably, like SKP2 [ 33 36 37 38 ] , CSN5 was found to be overexpressed in cancers devoid of p27 [ 63 ] . However, our studies did not reveal any effect of MIB on CSN5 expression.

  • Markers such as C-reactive protein are also increasingly implicated in the pathogenesis of atherosclerosis.

  • An example of a protein that is implicated in a different class of functions, but is still related to defense mechanisms is the predicted restriction endonuclease from Pyrococcus . Generally, the functions of proteins for which accelerated evolution was detected and functional diversification inferred are compatible with the previously reported cases of accelerated evolution which is particularly prominent, for example, in the immune system [ 3].


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