Example sentences for: immunologic

How can you use “immunologic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Smoking incites an immunologic response to vascular injury, described as oxidative stress leading to lipid peroxidation, endothelial cell dysfunction, and foam cell proliferation in the tunica media [1,2].

  • A unifying feature of autoimmune disorders appears to be the loss of immunologic tolerance to self-antigens, and in many of these diseases there is evidence that T-cell tolerance has been broken.

  • Our inability to show an increase in X-chromosome skewing in females with autoimmunity does not eliminate this as an etiologic contributor to loss of immunologic tolerance.

  • purified subunits or inactivated virus vs. various forms of "live" expression) can determine the relative nature and extent of humoral and cell mediated immunologic responses.

  • Epidemiologically, HLA genotype partially accounts for inter-patient variation in disease severity or progression rates for such long-term viral infections as HIV, human T-cell lymphotropic virus, type 1 (HTLV-1), and hepatitis B and C [ 5 6 7 8 9 ] . Such associations can lead to mechanistic studies to test hypotheses about the immunologic basis of these associations [ 10 11 ] and could, in principle, be used to help predict individual prognoses [ 12 13 ] . At least one clinical study has shown that HLA genotype affects the immune response to a candidate HIV vaccine [ 14 ] . Vaccine designers have begun to take account of the HLA genotypes of potential recipients in choosing antigens for inclusion in a vaccine [ 15 ] , and it has been suggested that HLA genotype be considered in designing samples for inclusion in epidemiologic studies of anti-HIV immune response [ 12 ] . In evolutionary biology, the possibility that HLA heterozygotes are more resistant to infectious diseases is the basis for a leading hypothesis to explain the unparalleled diversity of HLA genes (and MHC genes in other vertebrates) and the maintenance of this diversity over long periods of evolutionary time [ 16 ] .


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