Example sentences for: immunogenicity

How can you use “immunogenicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The improved immunogenicity of the variant was not related to changes in the proteolytic capacity of the enzyme, because the variant exhibited 80% of the activity of the parent enzyme.

  • In rodents, intravenous injection of a non-targeted vector - viruses or plasmid preparations - induces mainly transfection in the liver and the spleen [ 1 2 ] . As of today, transfection of other large organs by viral vectors has not been accomplished in by way of systemic delivery [ 3 ] . The main inconveniences of intravenous administration of first generation adenoviral vectors are their immunogenicity [ 4 ] and hepatic toxicity [ 5 6 ] . The muscle as a large tissue mass is a candidate for production of recombinant protein, but the transfection is limited to the injection site.

  • As a result of this shortcoming, vaccine candidates are at present primarily examined with regard to their effects on set point viremia, disease progression, and their general immunogenicity, rather than with regard to the degree of protection against infection they confer.

  • Overall maximum titer levels vary, but the difference in immunogenicity between B. lentus subtilisin and BPN' Y217L has been seen in three separate guinea pig studies.

  • Immunization of Hartley strain guinea pigs showed that this single amino acid change created a T cell epitope where there was no detectable epitope before, and the presence of this epitope correlates with an improved immunogenicity in the variant.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast