Example sentences for: immunogenicity

How can you use “immunogenicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a result of this shortcoming, vaccine candidates are at present primarily examined with regard to their effects on set point viremia, disease progression, and their general immunogenicity, rather than with regard to the degree of protection against infection they confer.

  • Some heteroclitic tumor antigen peptides that showed highly improved antigenicity and immunogenicity in preclinical studies, and which also cross-reacted well with CTLs generated against the parental sequence, were tested in clinical trials.

  • The rationale behind this study was that acidic plaque environments increase the amount of D-alanyl LTA and promote its immunogenicity.

  • Animal models can play an essential role in guiding preclinical vaccine development, including in studies of preclinical vaccine safety, vaccine toxicity, and vaccine immunogenicity.

  • In rodents, intravenous injection of a non-targeted vector - viruses or plasmid preparations - induces mainly transfection in the liver and the spleen [ 1 2 ] . As of today, transfection of other large organs by viral vectors has not been accomplished in by way of systemic delivery [ 3 ] . The main inconveniences of intravenous administration of first generation adenoviral vectors are their immunogenicity [ 4 ] and hepatic toxicity [ 5 6 ] . The muscle as a large tissue mass is a candidate for production of recombinant protein, but the transfection is limited to the injection site.

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