Example sentences for: immunogenicity

How can you use “immunogenicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, the inference as to the degree of sterilizing immunity from the level of immunogenicity is limited by our lack of knowledge about the mechanisms of protection against infection as such [13].

  • In rodents, intravenous injection of a non-targeted vector - viruses or plasmid preparations - induces mainly transfection in the liver and the spleen [ 1 2 ] . As of today, transfection of other large organs by viral vectors has not been accomplished in by way of systemic delivery [ 3 ] . The main inconveniences of intravenous administration of first generation adenoviral vectors are their immunogenicity [ 4 ] and hepatic toxicity [ 5 6 ] . The muscle as a large tissue mass is a candidate for production of recombinant protein, but the transfection is limited to the injection site.

  • A candidate vaccine comprised of a fusion protein based on two antigens has been selected and is currently in pharmaceutical development under the sponsorship of this project, with the goal of evaluating the safety and immunogenicity in humans.

  • The immunogenicity of an enzyme can be increased, while maintaining the majority of its stability and proteolytic activity, by incorporating a single amino acid change.

  • Some heteroclitic tumor antigen peptides that showed highly improved antigenicity and immunogenicity in preclinical studies, and which also cross-reacted well with CTLs generated against the parental sequence, were tested in clinical trials.


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