Example sentences for: immortalization

How can you use “immortalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The N9 murine microglia cell line was a gift kindly provided by Dr. P. Ricciardi-Castagnoli [ 62 ] . This cell line has been used extensively as a model for microglia [ 63 64 65 ] . These cells were derived by immortalization of day 13 embryonic brain cultures with a retrovirus carrying an activated v-myc oncogene.

  • Although telomerase expression is a hallmark of cancer, the mice lacking the RNA component of telomerase (mTERC) exhibit progressive telomere shortening and chromosomal instability associated with epithelial tumors [ 12 ] . Consistent with the established role of this enzyme in cell immortalization and cancer pathogenesis [ 18 ] , we did not find expression in normal cervix while it was abundantly present in all eight cell lines studied (Fig.

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