Words similar to imipenem
Example sentences for: imipenem
How can you use “imipenem” in a sentence? Here are some example sentences to help you improve your vocabulary:
The changes in molar absorptivities (Δε) used to quantitate products were (in M -1cm -1): nitrocefin, Δε 485 = 17,420; cephalothin, Δε 265 = -8,790; cefoxitin, Δε 265 = -7,000; cefaclor, Δε 280 = -6,410; imipenem, Δε 300 = -9,000; meropenem, Δε 293 = -7,600; biapenem, Δε 293 = -8,630; ampicillin, Δε 235 = -809; and penicillin G, Δε 235 = -936.
Patients with VAP caused by A. baumannii were treated with imipenem (21 patients) or, in the case of resistance to all other antibiotics, with colistin (14 patients).
Instead, we predict that the insertion of an aspartic acid into the active site at position 224 results in a change in the hydrogen bonding network in L1; this hydrogen bonding network is extensive in all metallo-β-lactamases that have been characterized crystallographically [ 37 42 44 45 48 49 62 63 ] . The N233D mutant also exhibited greatly reduced k cat values for biapenem and meropenem but not for imipenem or any of the other substrates tested.
On the other hand, experience with the drug in patients with cystic fibrosis, has shown only minimal nephrotoxicity [ 19 20 21 30 ] . Garnacho-Montero and coworkers [ 12 ] , in patients with VAP, observed that there was no significant difference in development of renal failure between colistin and imipenem.
Achieving clinical cure in 57% of cases, intravenous colistin was as effective as imipenem.