Words similar to imatinib
Example sentences for: imatinib
How can you use “imatinib” in a sentence? Here are some example sentences to help you improve your vocabulary:
Acquired resistance to kinase-targeted anticancer therapy has been most extensively studied with imatinib, an inhibitor of the aberrant BCR-ABL kinase, in chronic myelogenous leukemia (CML).
As a consequence, there have been additional dividends from the United States Federal Drug Administration approval of imatinib for treatment of BCR-ABL-positive CML.
Our results further demonstrate that an analogous mechanism of acquired resistance exists for imatinib and EGFR tyrosine kinase inhibitors (Table 3), despite the fact that the various agents target different kinases in distinct diseases.
Imatinib induces complete remission in most patients with CML in stable phase [1], and also has activity in CML that has progressed to blast crisis [2].
This was first appreciated in patients with CML treated with imatinib whose tumors developed resistance, and has been most extensively studied in that context.