Example sentences for: ileal

How can you use “ileal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • found significant decreases in active bile acid uptake when examining ileal brush border membrane vesicles [ 11 ] and proposed that altered viscosity of the ileal mucus was likely not a factor in ileal bile acid malabsorption associated with cystic fibrosis.

  • The correlation between zygosity and level of IBAT protein expression suggests a close relationship between the function of the CFTR chloride channel and the sodium-dependent ileal bile acid transporter.

  • Polyclonal rabbit antibodies were obtained from a commercial source (Research Genetics, Huntsville, AL) against a C-terminal 14 amino acid oligopeptide fragment of IBAT and purified by immuno-affinity chromatography as described [ 17 ] . The ileal tissue segments were snap-frozen in -70°C cold isopentane and then stored in -70°C until the tissues were processed.

  • Brush border membrane vesicles were prepared as described by deRooij [ 11 ] . Briefly, frozen ileal tissue fragments (20-25 mg) were thawed and homogenized in 100 μl of isotonic buffer (300 mM mannitol, 12 mM Tris-HCl, pH 7.1) using a Polytron homogenizer (Kinematica AG, Littau, Switzerland).

  • An alternative mechanism for the upregulation of IBAT in cystic fibrosis is that CFTR acts as a negative regulator of IBAT, as it does for the epithelial sodium channel [ 36 ] . As IBAT is a sodium-dependent apical membrane transporter, it might be regulated by CFTR, as is the epithelial sodium channel (ENaC) present in the apical membrane of the ileal enterocyte.


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