Example sentences for: ileal

How can you use “ileal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The ileal segments from 7-8 cm and 0-1 cm proximal to the ileocecal valve, respectively, from each animal were pooled and used for Western blots.

  • Untreated children and adults with cystic fibrosis excrete amounts of fecal bile acids similar to patients with ileal resections [ 20 21 ] . Based on kinetic studies, this increased fecal loss appears to be secondary to an interrupted enterohepatic circulation of bile acids [ 20 21 ] . Bile acid malabsorption in cystic fibrosis appears to be due in part to diminished secretion of pancreatic enzymes and the presence of un-hydrolyzed triglycerides.

  • Based on this evidence, we postulate that the more viscous mucus layer in the ileal crypts of individuals with cystic fibrosis limits access of luminal bile acids and micelles to the ileal crypt cells.

  • An alternative mechanism for the upregulation of IBAT in cystic fibrosis is that CFTR acts as a negative regulator of IBAT, as it does for the epithelial sodium channel [ 36 ] . As IBAT is a sodium-dependent apical membrane transporter, it might be regulated by CFTR, as is the epithelial sodium channel (ENaC) present in the apical membrane of the ileal enterocyte.

  • This may result in an altered programming of ileal stem cells and transit cells that give rise to absorptive enterocytes over-expressing IBAT protein.


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