Example sentences for: ile

How can you use “ile” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The C-terminal fragment was identified with SKI, a rabbit polyclonal antibody against the II-III loop of α 1S (Ala739-Ile752) previously characterized [ 34 ] . Cells were scrapped from tissue cultures dishes with cold PBS plus protease inhibitors and spun in a cold table-top centrifuge.

  • A missense mutation in Abcb7 (or hABC7 the human homolog of Atm1p), Ile400 → Met, has been implicated in X-linked sideroblastic anemia and ataxia [ 34], a disorder closely related to Friedreich's ataxia.

  • Like the emblem on its coat of arms, the Ile de la Cité takes the form of a boat, with the romantic tree-shaded place du Vert Galant as its prow pointing downstream.

  • All crystallographically characterized metallo-β-lactamases have a flexible amino acid chain that extends over the active site [ 37 42 44 45 46 47 48 49 ] . Previous NMR studies on CcrA have shown that this loop "clamps down" on substrate or inhibitor upon binding, and there is speculation that the distortion of substrate upon clamping down of the loop may drive catalysis [ 50 ] . The crystal structure of L1 showed that there is a large loop that extends over the active site, and modeling studies have predicted that two residues, Ile164 and Phe158, make significant contacts with large, hydrophobic substituents at the 2' or 6' positions on penicillins, cephalosporins, or carbapenems [ 37 ] . To test this prediction, Ile 164 and Phe158 were changed from large, hydrophobic residues to alanines to afford the I164A and F158A mutants.

  • The 18-mer duplex DNA encoding the insertion peptide (Ile-Asn-Asn-Glu-Thr-Ile) was ligated with Hpa1 digested pKK-RT66 in between codon 135 and 136.


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