Words similar to iix

Example sentences for: iix

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Although increased activities of citrate synthase [ 7 ] and SDH [ 2 3 ] have usually been demonstrated in the diaphragm in animal models of emphysema, fiber type has generally not been found to be significantly altered [ 1 2 3 7 ] . Only in one recent paper was a shift in MHC in emphysematous diaphragm demonstrated, but the histochemical technique used precluded the separation of IIb and IIx fibers [ 10 ] . Another study has shown increased expression of IIa at the expense of IIx MHC in emphysematous hamster scalene muscle with the use of MHC monoclonal antibodies, but there were none of the expected physiologic changes accompanying the shift [ 11 ] .
Although this shift toward a slower isoform is not as marked as that reported in humans [ 12 13 ] , in which MHC type I is upregulated and both IIa and IIx are downregulated, there is precedent for restricted MHC adaptation in rats.
A potential explanation of our results in relation to Kanbara's would be that there was a systematically greater concentration of IIb mRNA in IIb and IIb/IIx fibers than of other isoforms' mRNAs in their respective fibers.
It has been noted, for example, that IIx fibers have significantly higher SDH activity than IIb fibers [ 24 45 ] and, further, that IIb motor units are significantly more fatigue sensitive than IIx motor units [ 46 ] . Schiaffino et al.
This trend was most marked in the IIx isoform, for which the P value for increased expression in emphysematous versus control diaphragm reached 0.06.