Example sentences for: iix

How can you use “iix” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Subjectively, we saw no evidence of coexpression of fiber types I and IIa, but owing to the nature of antibody BF-35, which stains all except pure IIx fibers, we are unable to rule out the coexpression of IIx with any other isoform.

  • Although this shift toward a slower isoform is not as marked as that reported in humans [ 12 13 ] , in which MHC type I is upregulated and both IIa and IIx are downregulated, there is precedent for restricted MHC adaptation in rats.

  • Although increased activities of citrate synthase [ 7 ] and SDH [ 2 3 ] have usually been demonstrated in the diaphragm in animal models of emphysema, fiber type has generally not been found to be significantly altered [ 1 2 3 7 ] . Only in one recent paper was a shift in MHC in emphysematous diaphragm demonstrated, but the histochemical technique used precluded the separation of IIb and IIx fibers [ 10 ] . Another study has shown increased expression of IIa at the expense of IIx MHC in emphysematous hamster scalene muscle with the use of MHC monoclonal antibodies, but there were none of the expected physiologic changes accompanying the shift [ 11 ] .

  • MHC mRNA expression was analyzed by an MHC RT-PCR assay as described initially [ 19 ] and later adapted by its originators [ 22 ] . The assay is semi-quantitative, permitting accurate determination of relative amounts of mRNA of the embryonic, neonatal, I, IIa, IIx, and IIb MHC isoforms in muscle.

  • [ 27 ] found by in situ hybridization that 1.0% of fibers expressed only IIb and 8.8% coexpressed the IIx and IIb isoforms.


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