Example sentences for: iiia

How can you use “iiia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, we propose to study polymorphisms in genes involved in a number of systems and pathways related to stroke risk [ 5 ] : genes associated with coagulation factors and thrombophilia (Factor V, Prothrombin, Fibrinogen, Factor VII, Factor XIII, PAI-1, Thrombomodulin [TM], and MTHFR), as well as polymorphisms in genes that are involved in vascular reactivity (ACE), platelet activation/function (GpIIb/IIIa, GpIb IX-V, and GpIa/IIa), endothelial cell function (MTHFR, TM, VCAM-1, E-Selectin, L-Selectin, P-Selectin, and ICAM-1), inflammation (TNFα), lipid metabolism (Apo A1 and Apo E), and cell adhesion (VCAM-1, E-Selectin, L-Selectin, P-Selectin, and ICAM-1).

  • The candidate genes for this study include the gene encoding β-fibrinogen and the genes encoding platelet glycoprotein (GP) receptors Ia/IIa, Ib/IX/V, and IIb/IIIa.

  • Interestingly, although GP IIb/IIIa inhibitors were used in >60% of all patients, predominantly before intervention, major adverse clinical events were more common amongst those receiving the drug.

  • Glycoprotein (GP) IIb/IIIa inhibitors reduce not only procedural infarctions, but also major adverse clinical events in patients undergoing percutaneous coronary intervention.

  • The PURSUIT trial examined the role of eptifibatide, a platelet glycoprotein IIb/IIIa antagonist, in patients presenting with acute coronary syndromes without persistent ST-segment elevation.


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